Organic Chemistry
Which of the following compounds undergoes nucleophilic substitution reaction most easily?
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Single Choice
Rate of the reaction is fastest when $$Z$$ is:
A$$-Cl$$
Correct Answer
B$$-NH_2$$
C$$-OC_2H_5$$
D$$-OCOCH_3$$
Solution
$$Cl^-$$ is the best leaving group being the weakest nucleophile out of $$NH^-_2, Cl^-, OC_2H_5$$ and $$CH_3COO^-$$.
So, when $$Z$$ is $$Cl^-$$, the ion leaves faster thus making the reaction the fastest when $$Z$$ is $$Cl^-$$.
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