Subjective Type

Why can aromatic primary amines not be prepared by Gabriel phthalimide synthesis?

Solution

During Gabriel phthalimide synthesis, the reaction between phthalimide and ethanolic potassium hydroxide gives potassium salt of phthalimide.
The salt on heating with alkyl halide followed by alkaline hydrolysis gives corresponding primary amine.
Aromatic primary amines cannot be prepared by Gabriel phthalimide synthesis as aryl halides do not undergo nucleophilic substitution with the salt formed by phthalimide.


SIMILAR QUESTIONS

Organic Compounds Containing Nitrogen

Gabriel phthalimide reaction is used for the preparation of:

Organic Compounds Containing Nitrogen

Gabriel phthalimide synthesis is used in the preparation of primary amine from phthalimide which of the following reagent is not used during the process?

Organic Compounds Containing Nitrogen

Which of the following amines can be prepared by Gabriel phthalimide reaction?

Organic Compounds Containing Nitrogen

Ethylamine $$(C_2H_5NH_2)$$ can be obtained from N-ethylphthalimide on treatment with:

Organic Compounds Containing Nitrogen

The compound R is:

Organic Compounds Containing Nitrogen

The compound T is:

Organic Compounds Containing Nitrogen

Write short note on Gabriel phthalimide synthesis.

Organic Compounds Containing Nitrogen

Gabriel synthesis is used for the preparation of: a. $$1^{0}$$ amine b. $$2^{0}$$ amine c. $$3^{0}$$ amine d. All can be prepared

Organic Compounds Containing Nitrogen

The best method for preparing primary amines from alkyl halides without changing the number of carbon atoms in the chain is:

Organic Compounds Containing Nitrogen

Which of the following amines can be prepared by Gabriel synthesis.

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