Single Choice

A colourblind daughter is born when

AFather is colourblind, mother is normal
BMother is colourblind, father is normal
CMother is carrier, father is normal
DMother is carrier, father is colourblind
Correct Answer

Solution

Colourblindness is a X-linked recessive disorder. One copy of the affected gene in males in each cell is sufficient to cause the disorder (X$$^{c}$$Y). Females with two copies of the affected gene show the disorder (X$$^{c}$$X$$^{c}$$). Females heterozygous (X$$^{c}$$X) for this trait be normal but serve as a carrier of the disease. For a daughter to be affected, it should receive one copy of "X$$^{c}$$" allele from both parents which means that father should be affected and mother should be carrier or affected. This makes options A, B and C wrong because either mother or father is normal in those options. A carrier mother and colourblind father can give birth to a colourblind daughter because both parents carry one copy of affected allele. Correct option is "D".


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