Single Choice

Select the incorrect Statement regarding DNA replication with respect to the template strand

ALeading strand is formed in 5 $$\rightarrow$$ 3 direction.
BOkazaki fragments are formed in 5 $$\rightarrow$$ 3 direction.
CDNA polymerase catalyses polymerisation in 5 $$\rightarrow$$ 3 direction.
Correct Answer
DDNA polymerase catalyses palymerisation in 3 $$\rightarrow$$ 5 direction.

Solution

Since DNA polymerase requires a free 3' OH group for initiation of synthesis, it can synthesize in only one direction by extending the 3' end of the preexisting nucleotide chain. Hence, DNA polymerasemoves along the template strand in a 3'–5' direction, and the daughter strand is formed in a 5'–3' direction.
So, the correct answer is 'DNA polymerase catalyses polymerisation in 5
→→ 3 direction'

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