Genetics
Which of the following statement is not true for cancer cells in relation to mutations?
The sites in the gene at which the mutations occur with unusually high frequency are referred to as
Hot spots are the genetic loci which are more susceptible to mutations. The concept was given by Benzer who suggested that differential mutation rates for AT and GC are partly because of the surrounding bases. For example, misalignment of template during DNA replication produces long repeats which are highly prone to mutations. Smallest unit capable of undergoing recombination is called as recon. A recon consists of one to several mutons, which are the smallest unit of mutation. Palindromes are the DNA sequences that are read same in 5’ to 3’ direction on both strands; it does not affect the mutation rate. Correct answer is C.
Which of the following statement is not true for cancer cells in relation to mutations?
Which one of the following is a wrong statement regarding mutations?
What would happen, if in a gene encoding a polypeptide of 50 amino acids, $$25^{th}$$ codon (UAU) is mutated to UAA?
Choose the correct answer from the alternatives given : A DNA sequence undergoes three subsequent point mutations which result in subsequent changes in transcription of mRNA as shown below: Original mRNA : AUG CAU CUC ACG GAU UAG Point mutation 1: AUG CAU CUU ACG GUA UAG Point mutation 2 : AUG CAU GCU UAC - GGU AUA Point mutation 3 : AUG CAU GCU UAA GGU AUA Select the correct sequence of point mutations that occurred in the DNA.
The mutation of a purine to a pyramidine is known as
Enzymes X catalyzes hydrolysis of GTP into GDP. The GTP-bon from of Z transmits a signal that leads to cell proliferation. The GDP-bound from does not transmit any such signal. Mutations in X are in many cancers. Which of the following alterations of X are most likely to contribute to cancer ?
Why is nascent oxygen supported to be toxic to aerobic life forms?
A single base mutation in a gene may not 'always' result in loss or gain of function. Do you think the statement is correct? Defend your answer.
Frame shift mutation occurs when
Type of gene mutation which involves replacement of purine with pyrimidine or vice versa or the substitution of one type of base with another type of base is