Genetics
Which of the following statement is not true for cancer cells in relation to mutations?
Type of gene mutation which involves replacement of purine with pyrimidine or vice versa or the substitution of one type of base with another type of base is
Transduction is the transfer of genetic material from one strain to other via viral particles. The virus infects bacteria and released viral particles carry part of the bacterial genetic material which is then transferred to next host bacterium; option A is incorrect. Substitution of purine base for a pyrimidine base or substitution of pyrimidine base for a purine base is called as transversion. Hence, adenine is replaced with thymine/ uracil and guanine with cytosine which makes option B correct. Rearrangement of the chromosomal segment between two non-homologous chromosomes is called as translocation; option C is incorrect. Transcription is the process of synthesis of RNA using DNA template strand and is carried out by RNA polymerase; option D is incorrect.
Which of the following statement is not true for cancer cells in relation to mutations?
Which one of the following is a wrong statement regarding mutations?
What would happen, if in a gene encoding a polypeptide of 50 amino acids, $$25^{th}$$ codon (UAU) is mutated to UAA?
Choose the correct answer from the alternatives given : A DNA sequence undergoes three subsequent point mutations which result in subsequent changes in transcription of mRNA as shown below: Original mRNA : AUG CAU CUC ACG GAU UAG Point mutation 1: AUG CAU CUU ACG GUA UAG Point mutation 2 : AUG CAU GCU UAC - GGU AUA Point mutation 3 : AUG CAU GCU UAA GGU AUA Select the correct sequence of point mutations that occurred in the DNA.
The mutation of a purine to a pyramidine is known as
Enzymes X catalyzes hydrolysis of GTP into GDP. The GTP-bon from of Z transmits a signal that leads to cell proliferation. The GDP-bound from does not transmit any such signal. Mutations in X are in many cancers. Which of the following alterations of X are most likely to contribute to cancer ?
Why is nascent oxygen supported to be toxic to aerobic life forms?
A single base mutation in a gene may not 'always' result in loss or gain of function. Do you think the statement is correct? Defend your answer.
Frame shift mutation occurs when
The sites in the gene at which the mutations occur with unusually high frequency are referred to as