Single Choice

Which one of the following is a wrong statement regarding mutations?

ACancer cells commonly show chromosomal aberrations.
BUV and $$\gamma$$-rays are mutagens.
CChange in a single base pair of DNA does not cause mutation.
Correct Answer
DDeletion and insertion of base pairs cause frame-shift mutations.

Solution

Cancer cells commonly show chromosomal aberrations. Change in a single base pair of DNA cause mutations, which are called as point mutations. UV and $$\gamma$$-rays are mutagens, i.e., the mutation causing agents. Insertion or deletion of one or two bases changes the reading frame from the point of insertion or deletion. However, such mutations are referred to as frameshift insertion or deletion mutations. So, the statement in option C is wrong.

SIMILAR QUESTIONS

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Which of the following statement is not true for cancer cells in relation to mutations?

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What would happen, if in a gene encoding a polypeptide of 50 amino acids, $$25^{th}$$ codon (UAU) is mutated to UAA?

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Choose the correct answer from the alternatives given : A DNA sequence undergoes three subsequent point mutations which result in subsequent changes in transcription of mRNA as shown below: Original mRNA : AUG CAU CUC ACG GAU UAG Point mutation 1: AUG CAU CUU ACG GUA UAG Point mutation 2 : AUG CAU GCU UAC - GGU AUA Point mutation 3 : AUG CAU GCU UAA GGU AUA Select the correct sequence of point mutations that occurred in the DNA.

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The mutation of a purine to a pyramidine is known as

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Why is nascent oxygen supported to be toxic to aerobic life forms?

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A single base mutation in a gene may not 'always' result in loss or gain of function. Do you think the statement is correct? Defend your answer.

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The sites in the gene at which the mutations occur with unusually high frequency are referred to as

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Type of gene mutation which involves replacement of purine with pyrimidine or vice versa or the substitution of one type of base with another type of base is

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